For adults with moderately to severely active ulcerative colitis (UC).
WHY CHOOSE
TREMFYA®?
An important aspect of managing UC is to help visibly heal the lining of your colon and to treat your symptoms—
TREMFYA® can help with both.
FAST ACTING
In an induction study,*
Rapid symptom relief at
4 weeks
Some patients taking TREMFYA® experienced:
·fewer bowel movements
·less rectal bleeding (blood in stool)
more patients on TREMFYA®
(23% vs 8% of patients on placebo) achieved clinical remission at
12 weeks taking 200 mg starter intravenous (IV) infusions.†
*Results are from a clinical trial of patients with moderately to severely active UC: 421 patients received TREMFYA® 200 mg IV and 280 patients received placebo.
†Intravenous infusion (through a vein in the arm).
LONG LASTING
In a maintenance study of patients who responded in the
induction study,‡
more patients on TREMFYA® achieved clinical remission§ at one year:
- 50% of patients taking 200 mg subcutaneous maintenance injections|| vs 19% of patients taking placebo.
- 45% of patients taking 100 mg subcutaneous maintenance injections|| vs 19% of patients taking placebo.
‡ Results are from patients who achieved clinical response after 12 weeks of TREMFYA® induction and entered the maintenance trial: 190 patients received TREMFYA® 200 mg, 188 patients received TREMFYA® 100 mg, and 190 patients received placebo.
§ Clinical remission is based on frequency of bowel movements, fewer bloody stools, and endoscopy results.
||Subcutaneous injection (under the skin).
Some patients saw
100% VISIBLE HEALING
OF THEIR INTESTINAL LINING
In a maintenance study of patients who responded in the
induction study,‡
patients on TREMFYA® achieved endoscopic remission at one year, which is no visible signs of inflammation on the colon lining during endoscopy:
- 34% of patients taking TREMFYA® 200 mg subcutaneous maintenance injections vs 15% placebo.
- 35% of patients taking TREMFYA® 100 mg subcutaneous maintenance injections vs 15% placebo.
Visually assessed areas may not represent remission of the entire colon lining.
See the difference with endoscopic imagery¶:
Before
TREMFYA®
After one year on
TREMFYA®
¶The images are of sections of the colon from an actual patient who enrolled in the TREMFYA® UC induction and maintenance studies.
Individual results may vary.
Talk to your doctor to see if TREMFYA® is right for you.
TREMFYA®
LEGACY
14+
YEARS
of combined clinical research*
6+
YEARS
on the market across multiple indications
*Based on a clinical trial of TREMFYA® initiated in 2009.
TREMFYA® Safety Information
TREMFYA® may cause serious side effects, including:
- Serious allergic reactions. Stop using TREMFYA® and get emergency medical help right away if you develop any of the following symptoms of a serious allergic reaction:
- fainting, dizziness, feeling lightheaded (low blood pressure)
- swelling of your face, eyelids, lips, mouth, tongue or throat
- trouble breathing or throat tightness
- chest tightness
- skin rash, hives
- itching
- Infections. TREMFYA® is a medicine that may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with TREMFYA® and may treat you for TB before you begin treatment with TREMFYA® if you have a history of TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with TREMFYA®. Tell your healthcare provider right away if you have an infection or have symptoms of an infection, including:
- fever, sweats, or chills
- cough
- shortness of breath
- blood in your phlegm (mucus)
- muscle aches
- warm, red, or painful skin or sores on your body different from your psoriasis
- weight loss
- diarrhea or stomach pain
- burning when you urinate or urinating more often than normal
These are not all the possible side effects of TREMFYA®.
Please read the Important Safety Information located at the bottom of the screen and the Medication Guide for TREMFYA® to learn more about these and other risks for TREMFYA®. Discuss any questions you have with your doctor.
TREMFYA® may cause serious side effects, including:
- See “What is the most important information I should know about TREMFYA®?”
The most common side effects of TREMFYA® include:
- respiratory tract infections
- joint pain (arthralgia)
- fungal skin infections
- headache
- diarrhea
- herpes simplex infections
- injection site reactions
- stomach flu (gastroenteritis)
- bronchitis
These are not all the possible side effects of TREMFYA®. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
TREMFYA® may cause serious side effects, including:
- Serious allergic reactions. Stop using TREMFYA® and get emergency medical help right away if you develop any of the following symptoms of a serious allergic reaction:
- fainting, dizziness, feeling lightheaded (low blood pressure)
- swelling of your face, eyelids, lips, mouth, tongue or throat
- trouble breathing or throat tightness
- chest tightness
- skin rash, hives
- itching
- Infections. TREMFYA® is a medicine that may lower the ability of your immune system to fight infections and may increase your risk of infections. Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with TREMFYA® and may treat you for TB before you begin treatment with TREMFYA® if you have a history of TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with TREMFYA®. Tell your healthcare provider right away if you have an infection or have symptoms of an infection, including:
- fever, sweats, or chills
- cough
- shortness of breath
- blood in your phlegm (mucus)
- muscle aches
- warm, red, or painful skin or sores on your body different from your psoriasis
- weight loss
- diarrhea or stomach pain
- burning when you urinate or urinating more often than normal
These are not all the possible side effects of TREMFYA®.
Please read the Important Safety Information located at the bottom of the screen and the Medication Guide for TREMFYA® to learn more about these and other risks for TREMFYA®. Discuss any questions you have with your doctor.
TREMFYA® may cause serious side effects, including:
- See “What is the most important information I should know about TREMFYA®?”
The most common side effects of TREMFYA® include:
- respiratory tract infections
- joint pain (arthralgia)
- fungal skin infections
- headache
- diarrhea
- herpes simplex infections
- injection site reactions
- stomach flu (gastroenteritis)
- bronchitis
These are not all the possible side effects of TREMFYA®. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
